CHEM-5181

This is the new home for the CU-Boulder Graduate Course CHEM-5181: Mass Spectrometry and Chromatography

• The old web page is located here, and I'll be gradually move things over to this Wiki page, which is much easier to update.

Lectures

Introduction, Review, Igor

• Introduction and Review of Fundamentals
  • Regression Demo Program (PC Download)
  • Non-Parametric Regression Demo (Web)
  • Least Squares Polynomial Approximation Demo (Web)
  • Central Limit Theorem Demo (Web)
  • Fourier Synthesis Demo (Web)
  • Fourier Analysis Demo (Web)

• Introduction to Igor Pro

Mass Spectrometers

• TOFMS
  • Mass Spec. Oscilloscope Simulator (PC Download)

• Sector, FTICR, Orbitrap
  • Simulator of Magnetic Sector MS (PC Download)

• Quadrupoles
  • Video of Agilent LC/MS Quad
  • Video of Agilent LC/MS Triple Quad

• 3D Ion Traps

Ionization Sources

• Introduction and Electron Ionization
  • Ion Optics Simulator

• Electrospray and its Ion Chemistry (from Invited Lecturer Dr. Shuji Kato)

• Chemical Ionization
  • PTRMS Commercial Instrument
  • SYFT Commercial Instrument

• Invited Lecture: the Flowing Afterglow by Prof. Chuck dePuy

• Ionization IV: Bombardment, MALDI and Elemental

Detectors and Data Acquisition

• MS Detectors, A/D, Signal-to-Noise
  • Simulation of an Electron Multiplier
  • Simulation of an Analog-to-Digital Converter