CHEM-5181
From Jimenez Group Wiki
This is the new home for the CU-Boulder Graduate Course CHEM-5181: Mass Spectrometry and Chromatography
- The old web page is located here, and I'll be gradually move things over to this Wiki page, which is much easier to update.
Contents
Lectures
Introduction, Review, Igor
- Introduction and Review of Fundamentals
- Regression Demo Program (PC Download)
- Non-Parametric Regression Demo (Web)
- Least Squares Polynomial Approximation Demo (Web)
- Central Limit Theorem Demo (Web)
- Fourier Synthesis Demo (Web)
- Fourier Analysis Demo (Web)
Mass Spectrometers
- TOFMS
- Mass Spec. Oscilloscope Simulator (PC Download)
- Sector, FTICR, Orbitrap
- Simulator of Magnetic Sector MS (PC Download)
- 3D Ion Traps
Ionization Sources
- Introduction and Electron Ionization
- Electrospray and its Ion Chemistry (from Invited Lecturer Dr. Shuji Kato)
- Chemical Ionization
- Invited Lecture: the Flowing Afterglow by Prof. Chuck dePuy
- Ionization IV: Bombardment, MALDI and Elemental
Detectors and Data Acquisition
Homeworks
- [HW10/HW1_2010_Igor_Sector.docx HW1: Igor & Review of Fundamentals]
- [HW10/HW2_TOFMS.docx HW2: TOFMS]
- <a href="HW10/Raw_TOFAMS_Spec_only.itx">Data for Problem #1</a> (Igor Text File, save and double-click to open in Igor)
- [HW10/HW_MS_Resolution.docx">HW 3.1: mass spec resolution and accuracy]
- Quadrupole MS for donwload (Igor PXP format)
- [HW10/VLSPYDLTHK.xlsx Orbitrap MS for download] (Excel format)
- [HW10/HW_quadrupole_simul.docx HW3.2: Quadrupole MS simulation]
- Understanding the Quadrupole Mass Filter through Computer Simulation, Steel and Henchman, J. Chem. Ed. 75:1049-1054, 1998.
Labs
- Lab 1: MALDI-TOFMS:
- Lab 2: Electrospray MS:
- Lab 3: GC-MS of mixtures