Difference between revisions of "CHEM-5181"

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(Mass Spectrometers)
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** [http://www.youtube.com/watch?v=a5aLlm9q-Xc&feature=related Introd. animation of FTICR]
 
** [http://www.youtube.com/watch?v=a5aLlm9q-Xc&feature=related Introd. animation of FTICR]
  
* Quadrupoles
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* [http://cires.colorado.edu/jimenez/CHEM-5181/Lect/MS3_Mass_Analyzers_Quad.pdf Quadrupoles]
 
** [http://www.youtube.com/watch?v=PSFF6JJEFPE&NR=1 Video of Agilent GC/MS Triple Quad]
 
** [http://www.youtube.com/watch?v=PSFF6JJEFPE&NR=1 Video of Agilent GC/MS Triple Quad]
 
** [http://www.chem.agilent.com/en-US/Products/Instruments/ms/6100SeriesQuadrupoleLCMSSystems/Pages/6100_video.aspx Video of Agilent LC/MS Quad]
 
** [http://www.chem.agilent.com/en-US/Products/Instruments/ms/6100SeriesQuadrupoleLCMSSystems/Pages/6100_video.aspx Video of Agilent LC/MS Quad]
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** ''Prop: Quadrupole''
 
** ''Prop: Quadrupole''
  
* 3D Ion Traps
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* [http://cires.colorado.edu/jimenez/CHEM-5181/Lect/MS4_Mass_Analyzers_Q_Ion_Trap.pdf 3D Ion Traps]
  
 
=== Ionization Sources ===
 
=== Ionization Sources ===

Revision as of 17:13, 7 December 2010

This is the new home for the CU-Boulder Graduate Course CHEM-5181: Mass Spectrometry and Chromatography

  • The old web page is located here, and I'll be gradually move things over to this Wiki page, which is much easier to update.

Course Information

  • This course WILL be offered in Fall 2011, and WILL NOT be offered in Fall 2012
  • Fall 2010 Syllabus
  • Registering for the course:
    • Every CU student attending the course needs to register, either as (a) for grade; (b) for pass/fail; or (c) for "Audit/No Credit".
    • For non-CU students, you can register for the course through the [http://conted.colorado.edu/programs/access/ CU Continuing Education Program ("ACCESS"), again as either (a) for grade; (b) for pass/fail; or (c) for "Audit/No Credit".
  • Lectures: Tue & Thu 11:00-12:15, Ekeley W166
  • Labs: to be determined, based on the student and MS facility schedules (typically three Tue afternoons 1-3 pm)
  • Office hours: immediately after class on Tue & Thu
  • Textbooks:
    • de Hoffmann & Stroobant. Mass Spectrometry, Principles and Applications, 3rd. Ed. ISBN: 0471485667; Library: QD96.M3 H6413 2007
    • McLafferty & Turecek Interpretation of Mass Spectra, 4th Ed., ISBN: 0935702253; Library: QC454.M22 1993;

Lectures

Introduction, Review, Igor

Mass Spectrometers

Ionization Sources

  • Electrospray and its Ion Chemistry (from Invited Lecturer Dr. Shuji Kato)
    • Prop: ESI Source

Detectors and Data Acquisition

MS Interpretation

  • Interpretation of Mass Spectra III (The Molecular Ion)
  • Interpretation of Mass Spectra IV (Fragmentation Mechanisms)

Chromatography and Chemical Separations

Homeworks

Reference material for homeworks

HW on Intro and Review of Fundamentals

HW on TOFMS

HW on Resolution & Accuracy

HW on Quadrupoles

HW on Ion Optics

Labs

Lab 1: MALDI-TOFMS

Lab 2: Electrospray MS

Lab 3: GC-MS of mixtures